Regulation of MMP/TIMP Balance as Therapeutic Target in Pulmonary Diseases
Corinne A.E. Martin-Chouly,
Matrix metalloproteinases (MMPs) are a family of zinc endopeptidases, regulated by endogenous tissue inhibitors (TIMPs) and inducer (EMMPRIN). The demonstration of a functional role of MMPs in pulmonary diseases raises the possibility of therapeutic intervention targeting MMP/TIMP balance to prevent pathological processes.
Keywords: Pulmonary diseases, MMP, TIMP, EMMPRIN, regulation
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