Oxidative stress plays an important role in the pathogenesis of asthma. Recently several investigators have studied the effects of a variety of antioxidants on asthma. Antioxidants, including L-2- oxothiazolidine-4-carboxylic acid, reduce airway inflammation and hyper-responsiveness of asthma and may be novel therapeutic agents for asthma.
Keywords: Asthma, L-2-oxothiazolidine-4-carboxylic acid, N-acetyl-L-cysteine, NF-?B, oxidative stress, reactive oxygen species, antioxidant
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