Antioxidants as Novel Agents for Asthma

Author(s): Seoung J. Park , Yong C. Lee .

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 6 , Issue 2 , 2006

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Oxidative stress plays an important role in the pathogenesis of asthma. Recently several investigators have studied the effects of a variety of antioxidants on asthma. Antioxidants, including L-2- oxothiazolidine-4-carboxylic acid, reduce airway inflammation and hyper-responsiveness of asthma and may be novel therapeutic agents for asthma.

Keywords: Asthma, L-2-oxothiazolidine-4-carboxylic acid, N-acetyl-L-cysteine, NF-?B, oxidative stress, reactive oxygen species, antioxidant

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Article Details

Year: 2006
Page: [235 - 240]
Pages: 6
DOI: 10.2174/138955706775475948
Price: $58

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