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Mini-Reviews in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

Antioxidants as Novel Agents for Asthma

Author(s): Seoung J. Park and Yong C. Lee

Volume 6, Issue 2, 2006

Page: [235 - 240] Pages: 6

DOI: 10.2174/138955706775475948

Price: $65

Abstract

Oxidative stress plays an important role in the pathogenesis of asthma. Recently several investigators have studied the effects of a variety of antioxidants on asthma. Antioxidants, including L-2- oxothiazolidine-4-carboxylic acid, reduce airway inflammation and hyper-responsiveness of asthma and may be novel therapeutic agents for asthma.

Keywords: Asthma, L-2-oxothiazolidine-4-carboxylic acid, N-acetyl-L-cysteine, NF-?B, oxidative stress, reactive oxygen species, antioxidant


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