Development of Miltefosine for the Leishmaniases

Author(s): J. D. Berman.

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 6 , Issue 2 , 2006

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Abstract:

The leishmaniases consist of visceral and cutaneous syndromes present in > 30 endemic regions of the world. Miltefosine (hexadecylephosphocholine) is the first oral agent that is effective and tolerated for both visceral and cutaneous disease in several endemic regions, and represents a major advance in the treatment of these diseases.

Keywords: Miltefosine, visceral leishmaniasis, cutaneous leishmaniasis, efficacy, tolerance

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Article Details

VOLUME: 6
ISSUE: 2
Year: 2006
Page: [145 - 151]
Pages: 7
DOI: 10.2174/138955706775475993
Price: $58

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