Development of Miltefosine for the Leishmaniases

Author(s): J. D. Berman.

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 6 , Issue 2 , 2006

Become EABM
Become Reviewer


The leishmaniases consist of visceral and cutaneous syndromes present in > 30 endemic regions of the world. Miltefosine (hexadecylephosphocholine) is the first oral agent that is effective and tolerated for both visceral and cutaneous disease in several endemic regions, and represents a major advance in the treatment of these diseases.

Keywords: Miltefosine, visceral leishmaniasis, cutaneous leishmaniasis, efficacy, tolerance

Rights & PermissionsPrintExport Cite as

Article Details

Year: 2006
Page: [145 - 151]
Pages: 7
DOI: 10.2174/138955706775475993
Price: $58

Article Metrics

PDF: 9