Abstract
The use of plant miscellaneous preparations as an alternative to the treatment of cancer is a reality today due to the massive marketing of natural medicines versus anticancer chemotherapy. Although this situation is controversial and has not led to any significant benefits to patients, plants may play a significant role in the treatment of cancer. Historically, natural leads have evolved to some of the outstanding medicines used nowadays against lung, breast, and ovarian cancers, and leukemia. Natural products are still some of the important sources of new anticancer drugs. The Brazilian flora is considered one of the most diverse in the world, although not many large-scale pharmacological and phytochemical studies have been conducted so far. We present the updated status and results of the research developed by Brazilian research centers on anticancer active substances derived from natural sources, mainly plants from the Brazilian Rain Forests, focusing on their potential effectiveness and difficulties.
Keywords: biodiversity, screening, natural products, Amazon Rain Forest, Atlantic Forest
Anti-Cancer Agents in Medicinal Chemistry
Title: Cytotoxic Molecules from Natural Sources: Tapping the Brazilian Biodiversity
Volume: 6 Issue: 4
Author(s): Ivana Barbosa Suffredini, Antonio Drauzio Varella and Riad Naim Younes
Affiliation:
Keywords: biodiversity, screening, natural products, Amazon Rain Forest, Atlantic Forest
Abstract: The use of plant miscellaneous preparations as an alternative to the treatment of cancer is a reality today due to the massive marketing of natural medicines versus anticancer chemotherapy. Although this situation is controversial and has not led to any significant benefits to patients, plants may play a significant role in the treatment of cancer. Historically, natural leads have evolved to some of the outstanding medicines used nowadays against lung, breast, and ovarian cancers, and leukemia. Natural products are still some of the important sources of new anticancer drugs. The Brazilian flora is considered one of the most diverse in the world, although not many large-scale pharmacological and phytochemical studies have been conducted so far. We present the updated status and results of the research developed by Brazilian research centers on anticancer active substances derived from natural sources, mainly plants from the Brazilian Rain Forests, focusing on their potential effectiveness and difficulties.
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Cite this article as:
Barbosa Suffredini Ivana, Drauzio Varella Antonio and Naim Younes Riad, Cytotoxic Molecules from Natural Sources: Tapping the Brazilian Biodiversity, Anti-Cancer Agents in Medicinal Chemistry 2006; 6 (4) . https://dx.doi.org/10.2174/187152006777698187
DOI https://dx.doi.org/10.2174/187152006777698187 |
Print ISSN 1871-5206 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5992 |
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