Treatment of Recurrent Epistaxis in HHT

Author(s): U. W. Geisthoff, M. L. Fiorella, R. Fiorella.

Journal Name:Current Pharmaceutical Design

Volume 12 , Issue 10 , 2006

Abstract:

No optimal treatment modality is currently available for the treatment of recurrent epistaxis in HHT. In this review, different therapeutic concepts are discussed together with their pathophysiologic background. Patients often profess a preventive effect for nasal ointments and use packings which can be self-administed in the case of bleeding. An effective first-line treatment for physicians is the endonasal laser coagulation or argon plasma coagulation. A second line surgical procedure is septodermoplasty according to Saunders which can provide long-lasting relief if performed correctly. There have been reports on antifibrinolytic agents and hormones, but their efficacy has yet to be determined.

Keywords: Rendu-Osler-Weber disease, hereditary haemorrhagic telangiectasia, laser therapy, septodermoplasty, review

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Article Details

VOLUME: 12
ISSUE: 10
Year: 2006
Page: [1237 - 1242]
Pages: 6
DOI: 10.2174/138161206776361255
Price: $58

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