Theory of Substituent Effects: Recent Advances

Author(s): O. Exner, S. Bohm.

Journal Name: Current Organic Chemistry

Volume 10 , Issue 7 , 2006

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Abstract:

The review reports recent progress in the studies of substituent effects in isolated molecules, i. e. based either on the experimental gas-phase acidities (basicities), or on quantum chemical calculations. Attention was focused on cases when the results differed from or exceeded the traditional views: redefinition of the inductive effect, quantitative estimation of resonance, validity of the Hammett equation, interpretation of the ortho effect, additivity of the enthalpies of formation, acidity of carboxylic acids.

Keywords: basicities, Gas-Phase Acidities, Enthalpy, Quantum Chemical Calculations, Inductive Effect

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Article Details

VOLUME: 10
ISSUE: 7
Year: 2006
Page: [763 - 778]
Pages: 16
DOI: 10.2174/138527206776818892
Price: $58

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