Heterocyclic Nucleosides: Chemical Synthesis and Biological Properties

Author(s): Pedro Merino.

Journal Name: Current Medicinal Chemistry

Volume 13 , Issue 5 , 2006

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Abstract:

This update covers the literature for 2002 and 2003 dealing with the main topic of the previous review entitled Heterocyclic nucleosides. Chemical synthesis and biological properties and published in Curr. Med. Chem.-AIA, 2002, 1, 389. As in the first review, the papers in this survey are grouped by the type of the heterocyclic system that acts as a spacer between the hydroxymethyl group and the base moiety.

Keywords: immucillins, purine nucleoside phosphorylase (PNP) inhibitors, Condensation, antiviral agents, enantioselective synthesis, dithiolane

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Article Details

VOLUME: 13
ISSUE: 5
Year: 2006
Page: [539 - 545]
Pages: 7
DOI: 10.2174/092986706776055779
Price: $58

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