Abstract
In this report, we review the C- and N-functionalization of the pyridazine nucleus via palladium-catalyzed reactions (Suzuki, Stille, Sonogashira, carbonylation, Heck, Buchwald-Hartwig) in which carbon atoms of the pyridazine nucleus are involved. The efficient use of these reactions in synthetic strategies to build up polycyclic 1,2-diazines is also included.
Keywords: pyridazine nucleus, Negishi Reaction, Organometallic reagents, Chloropyridazines, brominated bicyclic fused system
Call for Papers in Thematic Issues
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Global food safety and security will continue to be a global concern for the next 50 years and beyond. Plant diseases have had a significant impact on food safety and security throughout the entire food chain, from primary production to consumption. While conventional chemical pesticides have been traditionally used for ...read more
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This research area combines theoretical computation and screening with machine learning for the design of covalent/metal organic framework-based catalysts, bridging the disciplines of organic chemistry, physical chemistry, computational chemistry, materials science, and machine learning. It covers several critical aspects: designing and synthesizing organic catalysts for improved performance, applying computational methods ...read more
Carbohydrates conversion in biofuels and bioproducts
Biomass pretreatment, hydrolysis, and saccharification of carbohydrates, and sugars bioconversion in biofuels and bioproducts within a biorefinery framework. Carbohydrates derived from woody biomass, agricultural wastes, algae, sewage sludge, or any other lignocellulosic feedstock are included in this issue. Simulation, techno-economic analysis, and life cycle analysis of a biorefinery process are ...read more
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