Immune Response to Parasitic Infections

Volume: 1

Protozoa

Indexed in: Chemical Abstracts, EBSCO, Ulrich's Periodicals Directory.

This Ebook provides an interesting and up-to-date overview of Parasite Immunology in terms of a survival battle between hosts and parasites, describing firstly how parasites interact with different B ...
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Immune Responses to Leishmania guyanensis Infection in Humans and Animal Models

Pp. 165-176 (12)

Catherine Ronet, Annette Ives, Eliane Bourreau, Nicolas Fasel, Pascal Launois and Slavica Masina

Abstract

Cutaneous Leishmaniasis caused by Leishmania guyanensis parasites is endemic in the North-East South America. There is, however, little information available concerning L. guyanensis infectivity and the immune response associated with different stages of the disease. In the following chapter we discuss the results obtained in human research with regard to the involvement of different types of immune cells and their roles during the development of infection with L. guyanensis parasites. We also provide a resume on the status of animal models of L. guyanensis infection and emphasize how essential these models are so as to increase our knowledge of immunopathogenesis in the host and thus provide an indispensable tool to test new therapeutic strategies.

Affiliation:

WHO-IRTC, Chemin des Boveresses 155,1066 Epalinges, Switzerland;