Theory in the Pathophysiology of Carcinogenesis

Indexed in: Scopus, EBSCO.

This e-book explains the essential role of angiogenesis in the progression and spread of the neoplasm, including the mechanics of initial carcinogenesis in promoting malignant transformation. The ...
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Basic and Implied Formulation of Tumor Angiogenesis as Template Constructs

Pp. 52-62 (11)

Lawrence M. Agius


Aberrant recognition of receptivity events in the vascular endothelial growth factor cascade involves an excessive response in terms of vascular endothelial cell proliferation beyond the simple dynamics of a purely angiogeneic adaptive response. The implicit development of malignancy as a term of reference with regard to the pathogenesis of malignancy is a further documented or registered imprint towards the evolution of systems to spread based on such angiogenesis.


angiogenesis, template, adaptive response.


Department of Pathology, University of Malta Medical School Mater Dei Hospital, MALTA EUROPE.