Frontiers in Medicinal Chemistry

Volume: 1

Editor(s): Atta-ur-Rahman and Allen B. Reitz

Co-Editor(s): M. Iqbal Choudhary and Cheryl P. Kordik

Indexed in: Scopus, EMBASE, Genamics JournalSeek and EMBiology

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Frontiers in Medicinal Chemistry is a book series devoted to the review of areas of important topical interest to medicinal chemists and others in allied disciplines. Frontiers in Medicinal Chemistry ...
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Preface  promotion: free to download

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Atta-ur-Rahman, M. Iqbal Choudhary, Allen B. Reitz and Cheryl P. Kordik



Targeting Protein Kinases for Bone Disease: Discovery and Development of Src Inhibitors  Open Access Plus

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Chester A. Metcalf, Marie Rose van Schravendijk, David C. Dalgarno and Tomi K. Sawyer



Inhibitors of Matrix Metalloproteinases: Design, Structure and Therapeutic Applications  Open Access Plus

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Jerry W. Skiles, Nina C. Gonnella and Arco Y. Jeng



Mechanism-based Inhibition of Metalloproteinases

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Selective COX-2 Inhibitors and Dual Acting Anti-inflammatory Drugs: Critical Remarks

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A. Bertolini, A. Ottani and M. Sandrini


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Protein Farnesyltransferase Inhibitors

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Semiramis Ayral-Kaloustian and Edward J. Salaski


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The Design of Competitive, Small-molecule Inhibitors of Coagulation Factor Xa

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Henry W. Pauls, William R. Ewing and Yong Mi Choi-Sledeski


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Current Therapies and Emerging Targets for the Treatment of Diabetes

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Allan S. Wagman and John M. Nuss


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Designed Enediyne Antitumor Agents

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G.B. Jones and F.S. Fouad


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The Expanding Role of NMR in Rational Drug Design

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Rickey P. Hicks and Daniel A. Nichols


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Recent Advances in PDE4 Inhibitors as Immunoregulators and Antiinflammatory Drugs

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Catherine Burnouf, Ingrid Devillers and Marie-Pierre Pruniaux


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Emerging β-Amyloid Therapies for the Treatment of Alzheimer's Disease

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Kelly A. Conway, Ellen W. Baxter, Kevin M. Felsenstein and Allen B. Reitz


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Constitutive Activity of Brain Serotonin Receptors: Inverse Agonist Activity of Antipsychotic Drugs

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Anil Purohit, Katharine Herrick-Davis and Milt Teitler


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Non-peptide Opioid Receptor Ligands - Recent Advances. Part I - Agonists

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Agnieszka Kaczor and Dariusz Matosiuk


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Nitric Oxide Therapies in Vascular Diseases

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E.M. Kurowska


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Strategies to Improve Stability and Bioavailability of Peptide Drugs

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Céline Adessi and Claudio Soto


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DNA Minor Groove Alkylators

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William A. Denny


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DNA-binding of Drugs Used in Medicinal Therapies

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G. Bischoff, S. Hoffmann and R. Zhdanov


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The Contribution of Combinatorial Chemistry to Lead Generation: An Interim Analysis

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Anton E.P. Adang and Pedro H.H. Hermkens


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New Paradigms in Drug Design and Discovery

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Joseph J. Barchi and Nouri Neamati


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Author Index  promotion: free to download

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Atta-ur-Rahman and Allen B. Reitz



Subject Index  promotion: free to download

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Atta-ur-Rahman and Allen B. Reitz