Frontiers in Natural Product Chemistry

Volume: 1

Indexed in: EBSCO.

“Frontiers in Natural Product Chemistry” is an Ebook series devoted to publishing the latest and most important advances in natural product chemistry. The Ebook series covers all aspects of ...
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Nature as Source and Inspiration for the Synthesis of New Anticancer Drugs

Pp. 51-54 (4)

Daniele Passarella, Alessandra Giardini, Giordano Lesma, Alessandra Silvani and Bruno Danieli

Abstract

The bifunctional taxoid-colchicinoid hybrids were synthesised and evaluated in assays of cytotoxicity and tubulin assembly/disassembly. All compounds showed a high degree of cytotoxicity.

Affiliation:

Dipartimento di Chimica Organica e Industriale, Universita degli Studi di Milano, Via Venezian, 21 - 20133 Milano, Italy.