Galantamine, a Natural Product for the Treatment of Alzheimer's Disease
Pp. 76-105 (30)
Luis Marco and Maria do Carmo Carreiras
Galantamine is a natural product that has attracted the interest of a number of researchers in a collaborative effort aimed at designing novel biologically active compounds for the treatment of Alzheimer's disease. In this article we review and update the syntheses of racemic and enantiomerically pure galantamine.
Galantamine, biogenetic-type synthesis, total synthesis, phenolic oxidative coupling, para-ortho coupling, PIFA, potassium ferricyanide, intramolecular heck reaction
Instituto de Quimica Organica General (CSIC), C/ Juan de la Cierva, 3, 28006-Madrid, Spain.