Particles from Gas-Saturated Solutions and Related Methods for Particle Engineering
Pp. 29-40 (12)
A. R. Sampaio de Sousa and Catarina M. M. Duarte
One of the most promising methods for particle engineering using supercritical fluids is the PGSS –
Particles from gas saturated solutions and derived methods. It has been used to micronized drugs and active
compounds and to produce composite particles, mainly for pharmaceutical applications, however food
applications are starting to arise among experimental work with potential for industrial applications. The
morphology and size of the particles obtained is diverse depending on the system used, but they are usually in a
micro-nano size range. This chapter presents an overview of the basic principles of the method, several
developments that were further undertaken, and a compilation of different examples and systems.
Instituto de Tecnologia Quimica e Biologica, Universidade Nova de Lisboa, Avenida da Republica, Estacao Agronomica Nacional, 2780-157 Oeiras, Portugal.