Advances in Biomedical Sciences and Engineering

Advances in Biomedical Sciences and Engineering

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This authoritative reference provides update information on the fundamental aspects and applications of biomaterials and biomedical sciences. It includes nickel-titanium alloys with superelasticity ...
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Strontium Containing Bioactive Bone Cement for Orthopedic Applications

Pp. 69-81 (13)

Zhaoyang Li, Keith Dip-Kei Luk and William Weijia Lu

Abstract

Strontium (Sr) and related compounds have become more attractive in the prevention and treatment of osteoporosis. Previously, we developed a novel bioactive bone cement, which mainly composed of strontium-containing hydroxyapatite (Sr-HA) filler and bisphenol A diglycidylether dimethacrylate (Bis-GMA) resin. This bone cement is superior to conventional polymethylmethacrylate (PMMA) bone cement in bioactivity, biocompatibility, and osseointegration. It also has shown sufficient mechanical strength properties for its use in percutaneous vertebroplasty (PVP) and total hip replacement (THR). In this chapter, we reviewed the in vitro, in vivo, and clinical evidence for the effectiveness of this bioactive bone cement.

Affiliation:

Department of Orthopedics and Traumatology, The University of Hong Kong, Hong Kong.