Role of the Phytochemical Compounds like Modulators in Gut Microbiota and Oxidative Stress

(E-pub Ahead of Print)

Author(s): Yordan Martínez, Dairon Más, Cesar Betancur, Kefyalew Gebeyew, Tolulope Adebowale, Tarique Hussain, Wensheng Lan, Xinghua Ding*.

Journal Name: Current Pharmaceutical Design

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Background: Currently, daily consumption of green herb functional food or medicinal herbs has gained many followers worldwide as a way of life or even as an alternative to the use of synthetic medicines. Phytochemicals, which are series of compounds of relatively complex structures and restricted distribution in plants, usually perform the defensive functions for plants against insects, bacteria, fungi or other pathogenic factors. A series of studies have found their effectiveness in the treatment or prevention of the systemic diseases such as autoimmune diseases, cancer, neurodegenerative diseases, Crohn's disease and so on.

Objective: This review has literature systematized the mechanisms of the phytochemicals to react against unique free radicals and prevent the oxidative stress and also summarized their role on gut microbiota inhibiting bacterial translocation and damage to the intestinal barrier and improving the intestinal membrane condition.

Conclusion: The gut microbiota modulation and antioxidant activities of the phytochemicals shall be emphasized on the research of the active principles of the phytochemicals.

Keywords: phytochemical compounds, dietary, beneficial, oxidative stress, gut microbiota, modulators.

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(E-pub Ahead of Print)
DOI: 10.2174/1381612826666200515132218
Price: $95

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