Natural products received much attention through their importance and application. Indolizidine categorized as an alkaloid which has several biological activities. The synthesis of natural compounds such as indolizidines has attracted much attention from many chemists’ and researchers’ perspectives. There are many rooms to be extended in this subject; that is why synthesizing indolizidine 209I and (±)-indolizidine 209B as natural compounds have received much consideration. This review discloses the procedures and methodology to provide (±)-indolizidine 209I and 209B due to the importance of indolizidines.
Keywords: Natural products, Alkaloids, Biological active, Indolizidine 209I, (±)-Indolizidine 209B, Poisonous frogs
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