The substitution reaction of glycal (1,2-unsaturated cyclic carbohydrate derivative)
at C1 by allyl rearrangement in the presence of a catalyst is called Ferrier type-I rearrangement.
2,3-Unsaturated glycosides are usually obtained from glycals through Ferrier
type-I rearrangement, and their potential biological activities have gradually attracted
widespread attention of researchers. This review summarizes recent advances (2009-
present) in the application of various types of catalysts to Ferrier type-I rearrangement reactions,
including their synthesis, mechanism, and application of 2, 3-unsaturated glycosides.
Keywords: Synthesis, 2, 3-unsaturated glycoside, Ferrier type-I rearrangement, catalyst, mechanism, application, bioactive.
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