Recent Nano-based Therapeutic Intervention of Bioactive Sesquiterpenes: Prospects in Cancer Therapeutics

(E-pub Ahead of Print)

Author(s): Mohammad Azam Ansari*, Khan Farheen Badrealam, Asrar Alam, Saba Tufail, Gulshan Khalique, Mohammad Javed Equbal, Mohammad A. Alzohairy, Ahmad Almatroudi, Mohammad N. Alomary, Faheem Hyder Pottoo.

Journal Name: Current Pharmaceutical Design


In recent scenario, nanotechnology based therapeutics intervention has gained tremendous impetus all across the globe. Nano-based pharmacological intervention of various bioactive compounds has been explored on an increasing scale. Sesquiterpenes are major constituents of essential oils (EOs) present in various plant species which embodies intriguing therapeutic potentials. However, owing to their poor physico-chemical properties; they have pharmacological limitations. Recent advances in nano-based therapeutic interventions offer various avenues to improve their therapeutic applicability. Reckoning with these, the present review collates various nano-based therapeutic intervention of sesquiterpenes with prospective potential against various debilitating diseases especially cancer. In our viewpoint, considering the burgeoning advancement in the field of nanomedicine; in the near future, clinical applicability of these nano-formulated sesquiterpenes can be foreseen with great enthusiasm.

Keywords: Sesquiterpenes, nanoformulations, cancer, therapeutics

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Article Details

(E-pub Ahead of Print)
DOI: 10.2174/1381612826666200116151522
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