Sulphonamide: Distribution, Toxicology, Environmental Characteristics, and Analysis - A Review

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Author(s): Kirubanandam Grace Pavithra, Vasudevan Jaikumar, Ponnusamy Senthil Kumar*, PanneerSelvam SundarRajan.

Journal Name: Current Analytical Chemistry

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Abstract:

Background: Many antibiotics were widely used as medication based on their distinctive features. Among them, sulphonamides were commonly used, however their recalcitrant nature makes them difficult to dispose. Hence, their interaction with environment and analytic technique requires considerable attention globally.

Objective: Therefore, this review aimed to provide detailed discussion about environmental as well as human health behaviour and analytic techniques corresponding to sulphonamides.

Methods: Various results and discussion were extracted from technical journals and books published by different researchers from all over the world. The cited bibliographic references were intentionally investigated in order to extract relevant information related to proposed work.

Results: In this review, the determination techniques such as UV-spectroscopy, Enthalpimetry, Immunosensor, Chromatography, Chemiluminescence, Photoinduced fluorometric determination, Capillary electrophoresis for sulphonamide determination were discussed in detail. Among them, High performance liquid chromatography (HPLC) and UV-spectroscopy was effective and extensively used for screening sulphonamide.

Conclusion: Knowing the quantification and behaviour of sulphonamide in aqueous solution is mandatory to opt the suitable wastewater treatment required. Hence, choosing appropriate high precision and feasible screening techniques is necessary, which can be attained with this review.

Keywords: Pharmaceuticals, Antibiotics, Sulphonamides, Toxic, Detection, Chromatography

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Article Details

(E-pub Ahead of Print)
DOI: 10.2174/1573411016666200108150816
Price: $95