Role of Dietary Antioxidants in Neurodegenerative Diseases. Where are We Standing?

(E-pub Ahead of Print)

Author(s): Sena Bakir, Gizem Catalkaya, Fatma Duygu Ceylan, Haroon Khan*, Burcu Guldiken, Esra Capanoglu, Mohammad Amjad Kamal.

Journal Name: Current Pharmaceutical Design


This review presents the potential effects of dietary antioxidants on neurodegenerative diseases. The relationship of autoimmunity and antioxidants, as well as their preventive effect on neurodegenerative diseases are evaluated. The driven factors of neurodegeneration and the potential effects of natural antioxidants are summarized for Alzheimer’s disease, Parkinson’s disease, multiple sclerosis, spongiform encephalopathy, Huntington’s disease, and amyotrophic lateral sclerosis (ALS). The effect of oxidative stress on neurodegenerative diseases and regulative effect of antioxidants on oxidative balance is discussed. This review provides beneficial information for the possible cure of neurodegenerative diseases with dietary intake of antioxidants.

Keywords: Neurodegenerative Diseases, Dietary Components, Antioxidants, Immune System

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(E-pub Ahead of Print)
DOI: 10.2174/1381612826666200107143619
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