Catalytic Applications of Saccharin and its Derivatives in Organic Synthesis

Author(s): Bubun Banerjee*, Vaishali Bhardwaj, Amninder Kaur, Gurpreet Kaur, Arvind Singh.

Journal Name: Current Organic Chemistry

Volume 23 , Issue 28 , 2019

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Graphical Abstract:


Saccharin (1,2-benzisothiazol-3(2H)-one-1,1-dioxide) is a very mild, cheap, commercially available, water soluble, environmentally benign and edible Brønsted acidic substance. Recently, with other utilities, saccharin and its derivatives were employed as catalysts for various organic transformations. In this review, catalytic applicability of saccharin and its derivatives under various reaction conditions is summarized.

Keywords: Green and sustainable synthesis, metal-free organo-catalysis, saccharin, saccharin sulfonic acid, sodium saccharin, DMAPsaccharin, tetrazole-amino-saccharin.

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Article Details

Year: 2019
Page: [3191 - 3205]
Pages: 15
DOI: 10.2174/1385272823666191121144758

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