Login Register Cart 0
Generic placeholder image

Current Biotechnology

Editor-in-Chief

ISSN (Print): 2211-5501
ISSN (Online): 2211-551X

Back
Journal Home About Journal Editorial Board Journal Insight Current Issue Volumes/Issues
Subscribe
Research Article

Performance of High Molecular Weight Osmotic Solution for Opuntia Betacyanin Concentration by Forward Osmosis

Author(s): Ravichandran Rathna and Ekambaram Nakkeeran*

Volume 8, Issue 2, 2019

Page: [116 - 126] Pages: 11

DOI: 10.2174/2211550108666191025112221

Abstract

Background: Forward osmosis is a sustainable membrane process employed for concentrating thermo-sensitive compounds to minimize storage and transportation costs with improved shelf life.

Objective: In this study, the intervention of high molecular weight osmotic agents in the concentration of Opuntia betacyanin using forward osmosis was studied. Furthermore, the statistical model was used to estimate the probabilistic behavior of the forward osmosis process during concentration.

Methods: By using 2k-full factor analysis, the hydrodynamic variables, such as flow rate (50 and 150 mL/min) and temperature (20 and 50ºC) of the feed solution and osmotic agent solution (OAS) were selected. The study focused on inquiring and developing a statistically significant mathematical model using four independent variables on transmembrane flux, concentration factor and concentrate recovery.

Results: Betacyanin feed flow rate of 50 mL/min at 28ºC, and OAS flow rate of 150 mL/min at 50ºC were determined as optimal conditions with a 2.5-fold increase in total soluble solids for a processing time of 4 h. Furthermore, forward osmosis enhanced the betacyanin concentration from 898 to 1004 mg/L and 98.7% recovery with 0.40 L/m2h transmembrane flux with comparable improvement in its physicochemical characteristics. The lower p-value of the main effects on the responses validated the significance of the process parameters on betacyanin concentration.

Conclusion: The study suggested that a high molecular weight sucrose could be used as an osmotic agent for the concentration of Opuntia betacyanin during forward osmosis.

Keywords: Betacyanin, forward osmosis, cellulose acetate membrane, sucrose, concentration, molecular weight.

« Previous Next »
Graphical Abstract

[1]
Albano C, Negro C, Tommasi N, et al. Betalains, phenols and antioxidant capacity in cactus pear [Opuntia ficus-indica (L.) Mill.] fruits from Apulia (South Italy) genotypes. Antioxidants 2015; 4(2): 269-80.
[http://dx.doi.org/10.3390/antiox4020269] [PMID: 26783704]
[2]
Osorio-Esquivel O, Álvarez VB. Dorantes-Álvarez, & Giusti MM. Phenolics, betacyanins and antioxidant activity in Opuntia joconostle fruits. Food Res Int 2011; 44(7): 2160-8.
[http://dx.doi.org/10.1016/j.foodres.2011.02.011]
[3]
Scarpa ES, Emanuelli M, Frati A, et al. Betacyanins enhance vitexin-2-O-xyloside mediated inhibition of proliferation of T24 bladder cancer cells. Food Funct 2016; 7(12): 4772-80.
[http://dx.doi.org/10.1039/C6FO01130F] [PMID: 27812566]
[4]
Sreekanth D, Arunasree MK, Roy KR, Chandramohan Reddy T, Reddy GV, Reddanna P. Betanin a betacyanin pigment purified from fruits of Opuntia ficus-indica induces apoptosis in human chronic myeloid leukemia Cell line-K562. Phytomedicine 2007; 14(11): 739-46.
[http://dx.doi.org/10.1016/j.phymed.2007.03.017] [PMID: 17482444]
[5]
Wang CQ, Yang GQ. Betacyanins from Portulaca oleracea L. ameliorate cognition deficits and attenuate oxidative damage induced by D-galactose in the brains of senescent mice. Phytomedicine 2010; 17(7): 527-32.
[http://dx.doi.org/10.1016/j.phymed.2009.09.006] [PMID: 19879120]
[6]
Tyszka-Czochara M, Pasko P, Zagrodzki P, Gajdzik E, Wietecha-Posluszny R, Gorinstein S. Selenium supplementation of amaranth sprouts influences betacyanin content and improves anti-inflammatory properties via NFκB in murine RAW 264.7 macrophages. Biol Trace Elem Res 2016; 169(2): 320-30.
[http://dx.doi.org/10.1007/s12011-015-0429-x] [PMID: 26162623]
[7]
Song H, Chu Q, Yan F, Yang Y, Han W, Zheng X. Red pitaya betacyanins protects from diet-induced obesity, liver steatosis and insulin resistance in association with modulation of gut microbiota in mice. J Gastroenterol Hepatol 2016; 31(8): 1462-9.
[http://dx.doi.org/10.1111/jgh.13278] [PMID: 26699443]
[8]
Azeredo HM, Santos AN, Souza AC, Mendes KC, Andrade MIR. Betacyanin stability during processing and storage of a microencapsulated red beetroot extract. Am J Food Technol 2007; 2(4): 307-12.
[http://dx.doi.org/10.3923/ajft.2007.307.312]
[9]
Herbach KM, Rohe M, Stintzing FC, Carle R. Structural and chromatic stability of purple pitaya (Hylocereus polyrhizus [Weber] Britton & Rose) betacyanins as affected by the juice matrix and selected additives. Food Res Int 2006; 39(6): 667-77.
[http://dx.doi.org/10.1016/j.foodres.2006.01.004]
[10]
Das M, Saeid A, Hossain MF, Jiang GH, Eun JB, Ahmed M. Influence of extraction parameters and stability of betacyanins extracted from red amaranth during storage. J Food Sci Technol 2019; 56(2): 643-53.
[http://dx.doi.org/10.1007/s13197-018-3519-x] [PMID: 30906022]
[11]
Vieira Teixeira da Silva D, Dos Santos Baião D, de Oliveira Silva F, et al. Betanin, a Natural Food Additive: Stability, Bioavailability, Antioxidant and Preservative Ability Assessments. Molecules 2019; 24(3): 458.
[http://dx.doi.org/10.3390/molecules24030458] [PMID: 30696032]
[12]
Rodriguez-Saona LE, Wrolstad RE. Current protocols in food analytical chemistry 2001.
[13]
Nayak CA, Rastogi NK. Forward osmosis for the concentration of anthocyanin from Garcinia indica Choisy. Separ Purif Tech 2010; 71(2): 144-51.
[http://dx.doi.org/10.1016/j.seppur.2009.11.013]
[14]
Garcia-Castello EM, McCutcheon JR. Dewatering press liquor derived from orange production by forward osmosis. J Membr Sci 2011; 372(1-2): 97-101.
[http://dx.doi.org/10.1016/j.memsci.2011.01.048]
[15]
Nayak CA, Valluri SS, Rastogi NK. Effect of high or low molecular weight of components of feed on transmembrane flux during forward osmosis. J Food Eng 2011; 106(1): 48-52.
[http://dx.doi.org/10.1016/j.jfoodeng.2011.04.006]
[16]
Durakovic B. Design of experiments application, concepts, examples: State of the art. Period Eng Nat Sci 2017; 5(3): 421-39.
[17]
Khayet M, Sanmartino JA, Essalhi M, García-Payo MC, Hilal N. Modeling and optimization of a solar forward osmosis pilot plant by response surface methodology. Sol Energy 2016; 137: 290-302.
[http://dx.doi.org/10.1016/j.solener.2016.07.046]
[18]
Ravichandran R, Ekambaram N. Assessment of factors influencing the concentration of betacyanin from Opuntia ficus-indica using forward osmosis: Concentration of betacyanin using forward osmosis. J Food Sci Technol 2018; 55(7): 2361-9.
[http://dx.doi.org/10.1007/s13197-018-3149-3] [PMID: 30042550]
[19]
Shah M, Chuttani K, Mishra AK, Pathak K. Oral solid compritol 888 ATO nanosuspension of simvastatin: optimization and biodistribution studies. Drug Dev Ind Pharm 2011; 37(5): 526-37.
[http://dx.doi.org/10.3109/03639045.2010.527983] [PMID: 21128704]
[20]
Rao P, Pattabiraman TN. Reevaluation of the phenol-sulfuric acid reaction for the estimation of hexoses and pentoses. Anal Biochem 1989; 181(1): 18-22.
[http://dx.doi.org/10.1016/0003-2697(89)90387-4] [PMID: 2817377]
[21]
Spector T. Refinement of the Coomassie blue method of protein quantitation: A simple and linear spectrophotometric assay for ≤ 0.5 to 50 μg of protein. Anal Biochem 1978; 86(1): 142-6.
[http://dx.doi.org/10.1016/0003-2697(78)90327-5] [PMID: 655375]
[22]
Ainsworth EA, Gillespie KM. Estimation of total phenolic content and other oxidation substrates in plant tissues using Folin-Ciocalteu reagent. Nat Protoc 2007; 2(4): 875-7.
[http://dx.doi.org/10.1038/nprot.2007.102] [PMID: 17446889]
[23]
Zhishen J, Mengcheng T, Jianming W. The determination of flavonoid contents in mulberry and their scavenging effects on superoxide radicals. Food Chem 1999; 64(4): 555-9.
[http://dx.doi.org/10.1016/S0308-8146(98)00102-2]
[24]
Garcia EJ, Oldoni TL, Alencar SMD, Reis A, Loguercio AD, Grande RHM. Antioxidant activity by DPPH assay of potential solutions to be applied on bleached teeth. Braz Dent J 2012; 23(1): 22-7.
[http://dx.doi.org/10.1590/S0103-64402012000100004] [PMID: 22460310]
[25]
Yetilmezsoy K, Demirel S, Vanderbei RJ. Response surface modeling of Pb(II) removal from aqueous solution by Pistacia vera L.: Box-Behnken experimental design. J Hazard Mater 2009; 171(1-3): 551-62.
[http://dx.doi.org/10.1016/j.jhazmat.2009.06.035] [PMID: 19577844]
[26]
Babu BR, Rastogi NK, Raghavarao KSMS. Effect of process parameters on transmembrane flux during direct osmosis. J Membr Sci 2006; 280(1-2): 185-94.
[http://dx.doi.org/10.1016/j.memsci.2006.01.018]

Rights & Permissions Print Cite
Article Metrics
25
4
© 2024 Bentham Science Publishers | Privacy Policy