C-N Bond Forming Reactions for the Synthesis of Five-membered N-heterocycles using Copper Catalysis

(E-pub Ahead of Print)

Author(s): Navjeet Kaur*, Pooja Grewal, Neha Ahlawat, Pranshu Bhardwaj, Meenu Devi, Yamini Verma, Nirmala Kumari Jangid.

Journal Name: Current Organocatalysis

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Abstract:

In recent years, the field of heterocyclic chemistry has been revolutionized with the use of transition metal catalysts. To achieve greater levels of molecular complexity and better functional group compatibilities, various research groups have focused on the development of general protocols which use easily available starting substrates under mild reaction conditions. This goal involved the introduction of molecular rearrangement steps into transition metal-catalyzed cycloisomerization reactions. These methods have an important advantage, in comparison to alternative pathways, in the synthesis of heterocyclic compounds with new substituents. This manuscript reported the synthesis of nitrogen- containing five-membered heterocycles usingcopper catalysts.

Keywords: Copper, Catalysis, Heterocycles, Nitrogen, Pesticides, Synthesis

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Article Details

(E-pub Ahead of Print)
DOI: 10.2174/2213337206666191022105221

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