Ovarian Cancer-Challenges and Innovations

Ovarian Cancer-Challenges and Innovations

This informative book provides a wealth of information on ovarian cancer. The book opens with a discussion of contemporary management of this disease with commentary on surgery and clinical trials: ...
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Pathology of Ovarian Cancer

Pp. 46-105 (60)

Jessica Beyda and Sedef Everest

Abstract

Ovarian cancer is the fifth leading cause of cancer death in American women. The term ‘ovarian cancer’ is loosely used by laymen to refer to ovarian malignancies from all classes of ovarian tumors (sex-cord stromal, germ cell and epithelial). In this chapter, we will discuss specifically the ovarian carcinomas, derived from epithelium, historically thought to be derived from the germinal epithelium but now shown to include fallopian tube epithelium. Ovarian carcinomas constitute a diverse group of neoplasms for which this chapter will discuss: clinical features including symptoms, gross findings, tumor histology with illustrations, immunohistochemical features used in working up the pathologic diagnosis, molecular features, and prognosis.

Keywords:

BRCA, Borderline, Clear cell, ERBB2, Endometrioid, Hereditary, HNPCC, KRAS, Low-grade, Mucinous, P53, PIK3CA, Pathogenesis, Prognosis, RRSO, Serous, STIC, PTEN, STIL.

Affiliation:

St. Francis Hospital Roslyn, N.Y., USA.