With the continuous exploitation of petroleum, Polycyclic Aromatic Hydrocarbons (PAHs), a diverse class of the organic pollutants with carcinogenicity, mutagenicity and teratogenicity, seriously endanger the ecological environment and public health. Pyrene, consisting of four benzene rings, is used as an indicator for PAH-contaminated waste monitoring and is ubiquitously found in oil-contaminated soils and water sediments. Thus, the most urgent task is to find a repair method that can degrade pyrene efficiently now. Bioremediation is widely applied in the degradation of pyrene due to its simplicity of operation, low environmental impact and low cost. This paper is a review of the repair methods of pyrene, including physical, chemical and bioremediation methods. In addition, it focuses on the methods, status quo, mechanisms and current problems that need to be solved in the bioremediation degradation of pyrene.