Current Designs and Developments of Fucoidan-based Formulations for Cancer Therapy

Author(s): Phuong H.L. Tran, Thao T.D. Tran*.

Journal Name: Current Drug Metabolism

Volume 20 , Issue 12 , 2019

Graphical Abstract:


Background: Natural nanostructure materials have been involved in antitumor drug delivery systems due to their biocompatibility, biodegradation, and bioactive properties.

Methods: These materials have contributed to advanced drug delivery systems in the roles of both bioactive compounds and delivery nanocarriers. Fucoidan, a valuable ocean material used in drug delivery systems, has been exploited in research on cancer and a variety of other diseases.

Results: Although the uniqueness, structure, properties, and health benefits of fucoidan have been mentioned in various prominent reviews, current developments and designs of fucoidan-based formulations still need to be assessed to further develop an effective anticancer therapy. In this review, current important formulations using fucoidan as a functional material and as an anticancer agent will be discussed. This article will also provide a brief principle of the methods that incorporate functional nanostructure materials in formulations exploiting fucoidan.

Conclusion: Current research and future perspectives on the use of fucoidan in anticancer therapy will advance innovative and important products for clinical uses.

Keywords: Fucoidan, drug delivery system, nanotechnology, functional nanomaterials, anticancer, nanocarriers.

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Article Details

Year: 2019
Page: [933 - 941]
Pages: 9
DOI: 10.2174/1389200220666191007154723
Price: $58

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