The interest in organophosphorus compounds with a C-P bond is due to their
wide use in various fields, especially in medicine and agrochemistry. Prominent examples
of anti-cancer, antibacterial, and anti-HIV agents are therapeutic candidates containing a
phosphonic acid group fragment. This review provides modern synthetic methods for obtaining
phosphorylated aromatic and heteroaromatic compounds with the participation of
complexes and salts of various metals developed in recent years as well modern protocol -
electrochemical synthesis which allows carrying out reactions at room temperature and
normal pressure with no additional oxidants or bases. Herein, we demonstrate new trends
and evolution of phosphorylation reactions in catalysis.
Keywords: Phosphorylation, C-H activation, catalysis, electrochemical synthesis, heteroaromatic compounds, organophosphorus compounds.
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