Arterial Hypertension in Type 2 Diabetes: Pathogenesis and Treatment
Pp. 160-172 (13)
Mustafa Kanat, Abdulhalim Senyigit and Muhammad A Abdul-Ghani
Diabetes and hypertension are increasing worldwide as an important public
health problem. There is a fairly common ground that combines diabetes and
hypertension. Especially insulin resistance is very important in this respect.
Epidemiological data and randomized clinical trials indicate that appropriate treatment
of diabetes and hypertension provides a significant reduction in cardiovascular events.
For this reason, it is extremely important that these two diseases be handled separately.
ACE inhibitors, ARB blockers, calcium channel blockers and thiazide diuretics are the
preferred agents in these patients. For patients with albuminuria, ARB or ACEI should
be preferred for renoprotective effects. In patients with resistant hypertension,
aldosterone antagonists therapy may be added to present therapy.
Aldosterone antagonists therapy, Albuminuria, Arterial hypertension,
ACE inhibitors, ARB blockers, Calcium channel blockers, Insulin resistance,
Resistant hypertension, Type 2 diabetes, Thiazide diuretics.
Division of Diabetes, Department of Internal Medicine, University of Istanbul Medeniyet, Goztepe Training and Research Hospital, Istanbul, Turkey.