Introduction: The N-heterocyclic compounds have been extensively studied in pharmaceutical
industries. Furthermore, syntheses of such compounds employing organo-catalyst have been associated
with sustainable technology.
Methods: The synthesis of new, stable ionic liquids and their catalytic applications in one-pot multicomponent
Biginelli reaction is presented. The method provides broad substrate scope, yielding the
corresponding 3,4-dihydropyrimidin-2(1H)-ones and 3,4-dihydropyrimidin-2(1H)-thiones, in good to
excellent yields, respectively.
Results and Conclusion: The developed reactions are associated with certain advantages, short reaction
time and sustainable conditions. The protocol has advantages eco-friendly procedure, recovery and
reusability of catalyst, which showed consistent activity.