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Current Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 0929-8673
ISSN (Online): 1875-533X

Perspectives in Medicinal Chemistry

Molecular Biomarkers of Disease for Diagnosis and Drug Development

Author(s): Rita Berisio*

Volume 26, Issue 24, 2019

Page: [4498 - 4500] Pages: 3

DOI: 10.2174/092986732624190927115301

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Sandomenico, A.; Ruvo, M. Targeting Nodal and Cripto-1: perspectives inside dual potential theranostic cancer biomarkers. Curr. Med. Chem., 2019. in press
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McNitt, D.H.; Van De Water, L.; Marasco, D.; Berisio, R.; Lukomski, S. Streptococcal Collagen-like Protein 1 Binds Wound Fibronectin: Implications in Pathogen Targeting. Curr. Med. Chem., 2019. in press
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De Maio, F.; Squeglia, F.; Goletti, D.; Delogu, G. The Mycobacterial Surface Protein HBHA: a Promising Biomarker for Tuberculosis. Curr. Med. Chem., 2019. in press
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Phan, L.M.T.; Tufa, L.T.; Kim, H.J.; Lee, J.; Park, T.J. Trends in Diagnosis for Active Tuberculosis Using Nanomaterials. Curr. Med. Chem., 2019. in press
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Gula, G.; Dorotkiewicz-Jach, A.; Korzekwa, K.; Valvano, M.A.; Drulis-Kawa, Z. Complex Signaling Networks Controlling Dynamic Molecular Changes in Pseudomonas aeruginosa Biofilm. Curr. Med. Chem., 2019. in press
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Larrouy-Maumus, G. Lipids as pathogenesis biomarkers. Curr. Med. Chem., 2019. in press
[9]
Squeglia, F.; Bachert, B.; De Simone, A.; Lukomski, S.; Berisio, R. The crystal structure of the streptococcal collagen-like protein 2 globular domain from invasive M3-type group A Streptococcus shows significant similarity to immunomodulatory HIV protein gp41. J. Biol. Chem., 2014, 289(8), 5122-5133.
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Lukomski, S.; Bachert, B.A.; Squeglia, F.; Berisio, R. Collagen-like proteins of pathogenic streptococci. Mol. Microbiol., 2017, 103(6), 919-930.
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McNitt, D.H.; Choi, S.J.; Allen, J.L.; Hames, R.A.; Weed, S.A.; Van De Water, L.; Berisio, R.; Lukomski, S. Adaptation of the group A Streptococcus adhesin Scl1 to bind fibronectin type III repeats within wound-associated extracellular matrix: implications for cancer therapy. Mol. Microbiol., 2019. in the press.
[12]
Esposito, C.; Pethoukov, M.V.; Svergun, D.I.; Ruggiero, A.; Pedone, C.; Pedone, E.; Berisio, R. Evidence for an elongated dimeric structure of heparin-binding hemagglutinin from Mycobacterium tuberculosis. J. Bacteriol., 2008, 190(13), 4749-4753.
[13]
Squeglia, F.; Ruggiero, A.; De Simone, A.; Berisio, R. A structural overview of mycobacterial adhesins: Key biomarkers for diagnostics and therapeutics. Protein Sci., 2018, 27(2), 369-380.
[14]
Squeglia, F.; Ruggiero, A.; Berisio, R. Chemistry of Peptidoglycan in Mycobacterium tuberculosis Life Cycle: An off-the-wall Balance of Synthesis and Degradation. Chemistry, 2018, 24(11), 2533-2546.
[15]
Squeglia, F.; Ruggiero, A.; Berisio, R. Exit from mycobacterial dormancy: a structural perspective. Curr. Med. Chem., 2015, 22, 1698-1709.
[16]
Squeglia, F.; Romano, M.; Ruggiero, A.; Berisio, R. Molecular players in tuberculosis drug development:another break in the cell wall. Curr. Med. Chem., 2017, 24, 3954-3969.

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