Background: One of the many debated topics in inflammation research is
whether this scenario is really an accelerated form of human wound healing and immunityboosting
or a push towards autoimmune diseases. The answer requires a better understanding
of the normal inflammatory process, including the molecular pathology underlying the
possible outcomes. Exciting recent investigations regarding severe human inflammatory
disorders and autoimmune conditions have implicated molecular changes that are also
linked to normal immunity, such as triggering factors, switching on and off, the influence
of other diseases and faulty stem cell homeostasis, in disease progression and development.
Methods: We gathered around and collected recent online researches on immunity, inflammation,
inflammatory disorders and AMPK. We basically searched PubMed, Scopus
and Google Scholar to assemble the studies which were published since 2010.
Findings: Our findings suggested that inflammation and related disorders are on the verge
and interfere in the treatment of other diseases. AMPK serves as a key component that prevents
various kinds of inflammatory signaling. In addition, our table and hypothetical figures
may open a new door in inflammation research, which could be a greater therapeutic
target for controlling diabetes, obesity, insulin resistance and preventing autoimmune diseases.
Conclusion: The relationship between immunity and inflammation becomes easily apparent.
Yet, the essence of inflammation turns out to be so startling that the theory may not be
instantly established and many possible arguments are raised for its clearance. However,
this study might be able to revea