The Latest Researches of Enzyme Inhibition and Multi-Target Drug Predictors in Medicinal Chemistry

Author(s): Guo-Ping Zhou.

Journal Name: Medicinal Chemistry

Volume 15 , Issue 6 , 2019

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Zhou, G.P. Impacts of computational biology to medicinal chemistry. Med. Chem., 2017, 13(6), 504-505.
Zhou, G.P. Impacts of biological science to medicinal chemistry. Curr. Top. Med. Chem., 2017, 17, 2335-2336.
Zhou, G.P. Editorial, Special issue: Current progress in structural bioinformatics of protein-biomolecule interactions. Med. Chem., 2015, 11(3), 216-217.
Jiang, Q.X. Structural variability in the RLR-MAVS pathway and sensitive detection of viral RNAs. Med. Chem., 2018.
[ Epub ahead of print]
Chen, W.; Liang, X.M.; Nong, Z.H.; Li, Y.X.; Pan, X.R.; Chen, C.X.; Huang, L.Y. The multiple applications and possible mechanisms of the hyperbaric oxygenation therapy. Med. Chem., 2018.
[ Epub ahead of print]
Zhou, G.P., and; Doctor, K. Subcellular location prediction of apoptosis proteins. Proteins Struct. Funct. Genet., 2002, 50, 44-48.
Cheng, X.; Xiao, X.; Chou, K.C. pLoc-mVirus: Predict subcellular localization of multi-location virus proteins via incorporating the optimal GO information into general PseAAC. Gene (Erratum: ibid., 2018. 644, 156-156), 2017, 628, 315-321
Cheng, X.; Zhao, S.G.; Lin, W.Z.; Xiao, X.; Chou, K.C. pLoc-mAnimal: Predict subcellular localization of animal proteins with both single and multiple sites. Bioinformatics, 2017, 33, 3524-3531.
Chou, K.C.; Cheng, X.; Xiao, X. pLoc_bal mEuk: Predict subcellular localization of eukaryotic proteins by general PseAAC and quasi-balancing training dataset. Med. Chem., 2018.
[ [Epub ahead of print].]
Huang, R.B.; Cheng, D.; Lu, B.; Liao, S.M.; Troy, F.A.; Zhou, G.P. The intrinsic relationship between structure and function of the sialyltransferase ST8Sia family members. Curr. Top. Med. Chem., 2017, 17, 2359-2369.
Zhou, G.P.; Huang, R.B.; Troy, F.A. 3D structural conformation and functional domains of polysialyltransferase ST8Sia IV required for polysialylation of neural cell adhesion molecules. Protein Pept. Lett., 2015, 22, 137-148.
Peng, L.X.; Liu, X.H.; Lu, B.; Liao, S.M.; Zhou, F.; Huang, J.M.; Chen, D.; Troy, II , F.A; Zhou, G.P.; Huang, R.B. The inhibition of polysialyltranseferase ST8SiaIV through Heparin binding to PolysialyltransferaseDomain (PSTD). Med. Chem., 2018.Dec 16.
[ [Epub ahead of print].]
Xiao, X.; Cheng, X.; Chen, G.; Mao, Q.; Chou, K.C. Bal mVirus: Predict subcellular localization of multi-label virus proteins by PseAAC and IHTS treatment to balance training dataset. Med. Chem., 2018 Dec 16.
[ [Epub ahead of print].]
Liao, S.M.; Shen, N.K.; Liang, G.; Lu, B.; Lu, Z.L.; Peng, L.X.; Zhou, F.; Du, L.Q.; Wei, Y.T.; Zhou, G.P.; Huang, R.B. Inhibition of α-amylase activity by Zn2+: insights from spectroscopy and molecular dynamics simulations. Med. Chem., 2018.
[ [Epub ahead of print].]
Si-Ming, L.; Ge, L.; Jing, Z.; Bo, L.; Li-Xin, P.; Qing-Yan, W.; Yu-Tuo, W.; Guo-Ping, Z.; Ri-Bo, H. Influence of calcium ions on the thermal characteristics of α-amylase from thermophilic Anoxybacillus sp. GXS-BL. Protein Pept. Lett., 2019, 26, 148-157.

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Article Details

Year: 2019
Page: [572 - 573]
Pages: 2
DOI: 10.2174/157340641506190826145925

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