Stroke is an acute neurologic disorder which can be life-threatening if left untreated or diagnosed
late. Various detecting techniques including neurologic imaging of the brain by computed
tomography or magnetic resonance imaging can facilitate diagnosis of stroke. However, according to
the recent advances in molecular detection techniques, new diagnostic and prognostic markers have
emerged. Exosomes as an extra cellar particle are one of these markers which can have useful diagnostic,
prognostic, and even therapeutic impact after stroke. We have previously discussed the role of
exosomes in cardiovascular disease and in the present review we focus on the most common cerebrovascular
disease. The aim of the present review is summarizing the recent diagnostic role of
exosomes which are specifically secreted during a stroke and can guide clinicians to better diagnosis
Keywords: microRNA, exosome, stroke, diagnosis, cerebrovascular disease, thrombosis.
Slam AU. Clinical pattern of stroke and distributions according to age, gender and potential risk factors. J Rawalpindi Medical College 2018; 22(S-1): 27-30.
Nazari-Shafti M-T. A Monocyte Inspired Guiding System: Targeting
of Exosomes to Ischemia Activated Microvascular Endothelium. The Thoracic and Cardiovascular Surgeon In: 2019. 67: p. (S 01)DGTHG-KV152.
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