G-quadruplex - Characterization of Functions and Potential Therapeutic Uses of Non-canonical DNA Structures

Author(s): Mattia Prosperi .

Journal Name: Current Medicinal Chemistry

Volume 26 , Issue 16 , 2019

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Cardon, L.R.; Harris, T. Precision medicine, genomics and drug discovery. Hum. Mol. Genet., 2016, 25(R2), R166-R172. [https://doi.org/10.1093/hmg/ddw246]. [PMID: 27538422].
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Han, H.; Hurley, L.H. G-quadruplex DNA: a potential target for anti-cancer drug design. Trends Pharmacol. Sci., 2000, 21(4), 136-142. [doi:10.1016/s0165-6147(00)01457-7].
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Biffi, G.; Tannahill, D.; McCafferty, J.; Balasubramanian, S. Quantitative visualization of DNA G-quadruplex structures in human cells. Nat. Chem., 2013, 5(3), 182-186. [doi:10.1038/nchem.1548].
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Chambers, V.S.; Marsico, G.; Boutell, J.M.; Di Antonio, M.; Smith, G.P.; Balasubramanian, S. High-throughput sequencing of DNA G-quadruplex structures in the human genome. Nat. Biotechnol., 2015, 33(8), 877-881.
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Estep, K.N.; Butler, T.J.; Ding, J.; Brosh, R.M. G4-interacting DNA helicases and polymerases: potential therapeutic targets. Curr. Med. Chem., 2019, 26(16), 2881-2897.
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Nayun, K. The interplay between G-quadruplex and Transcription. Curr. Med. Chem., 2019, 26(16), 2898-2917.
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Falabella, M.; Fernandez, R.J.; Johnson, F.B.; Kaufman, B.A. Potential roles for G-quadruplexes in mitochondria. Curr. Med. Chem., 2019, 26(16), 2918-2932.


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Article Details

VOLUME: 26
ISSUE: 16
Year: 2019
Page: [2879 - 2880]
Pages: 2
DOI: 10.2174/092986732616190820105842

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