Background: Shoulder joint dislocation is the most common dislocation of joints in the
body. To reduce the anterior shoulder dislocation, it is necessary to have analgesia and sedation.
Methods: In this randomized clinical trial, patients were divided into two equal groups. Group I received
midazolam-fentanyl (0.05 mg/kg fentanyl at a dose of 1 µg/kg) for 10 minutes and group II
received dexmedetomidine (1 µg/kg in the initial dose and then 0.2 µg/kg/h) for 10 minutes. The levels
of analgesia according to VAS criteria and the time to reach desired sedation were compared between
the two groups.
Results: A total of 60 patients participated in this study. The time to reach the desired sedation was
8.60 ± 2.3 minutes in the dexmedetomidine group and 11.27 ± 3.57 minutes in the midazolamfentanyl
group (p= 0.001). Also, the VAS score in both midazolam-fentanyl and dexmedetomidine
groups was 3.3 ± 1.24 and 2.57 ± 0.9, respectively. The differences were statistically significant
(p=0.015). There was significant relationship between the time to reach desired sedation and the level
of analgesia. Moreover, there was no significant difference between patient age and the time to reach
the desired level of analgesia. During this study, no side effect was observed.
Conclusion: The findings of this study show that dexmedetomidine provides a higher level of analgesia
than midazolam-fentanyl. Moreover, it was also shown that dexmedetomidine causes quicker
procedural sedation than midazolam-fentanyl.