Isolation, Synthesis and Medicinal Significance of Marine Pyridoacridine Alkaloids

Author(s): Saqlain Haider, Amar G. Chittiboyina*, Ikhlas A. Khan.

Journal Name: Current Organic Chemistry

Volume 23 , Issue 13 , 2019

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Graphical Abstract:


Abstract:

Pyridoacridine alkaloids, distributed in marine organisms have emerged as an important class of compounds due to their uniqure chemical architecture, diversity and medicinal significance. These alkaloids are reported to exhibit a wide array of biological activities like anti-cancer, anti-bacterial, ant-viral, anti-fungal and anti-parasitic activities. The present review highlights the isolation, synthesis and medicinal significance of this important class of pyridoacridine alkaloids.

Keywords: Pyridoacridine, biosynthesis, annulation, Boekelheide rearrangement, isolation, synthesis, anti-parasitic.

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VOLUME: 23
ISSUE: 13
Year: 2019
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DOI: 10.2174/1385272823666190725093517
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