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Current Organic Chemistry

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ISSN (Print): 1385-2728
ISSN (Online): 1875-5348

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General Review Article

Isolation, Synthesis and Medicinal Significance of Marine Pyridoacridine Alkaloids

Author(s): Saqlain Haider, Amar G. Chittiboyina * and Ikhlas A. Khan

Volume 23, Issue 13, 2019

Page: [1469 - 1495] Pages: 27

DOI: 10.2174/1385272823666190725093517

Price: $65

Abstract

Pyridoacridine alkaloids, distributed in marine organisms have emerged as an important class of compounds due to their uniqure chemical architecture, diversity and medicinal significance. These alkaloids are reported to exhibit a wide array of biological activities like anti-cancer, anti-bacterial, ant-viral, anti-fungal and anti-parasitic activities. The present review highlights the isolation, synthesis and medicinal significance of this important class of pyridoacridine alkaloids.

Keywords: Pyridoacridine, biosynthesis, annulation, Boekelheide rearrangement, isolation, synthesis, anti-parasitic.

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