Hydrogels are known as polymer-based networks with the ability to
absorb water and other body fluids. Because of this, the hydrogels are used
to preserve drugs, proteins, nutrients or cells. Hydrogels possess great
biocompatibility, and properties like soft tissue, and networks full of
water, which allows oxygen, nutrients, and metabolites to pass. Therefore,
hydrogels are extensively employed as scaffolds in tissue engineering.
Specifically, hydrogels made of natural polymers are efficient structures
for tissue regeneration, because of their mimic natural environment which
improves expression of cellular behavior.
Producing natural polymer-based hydrogels from collagen, hyaluronic acid
(HA), fibrin, alginate, and chitosan is a significant tactic for tissue
engineering because it is useful to recognize the interaction between
scaffold with a tissue or cell, their cellular reactions, and potential for
tissue regeneration. The present review article focused on injectable
hydrogels scaffolds made of biocompatible natural polymers with particular
features, the methods that can be employed to engineer injectable hydrogels
and their latest applications in tissue regeneration.