Cosmeceuticals are innovative emerging health and beauty aid products that combine the benefits of
cosmetic active ingredients and often innovative technological solutions of formulation and delivery. For decades,
phytocompounds have been used in cosmetics as sunscreen, moisturizing, antiaging, and skin-based therapy.
When compared to synthetic cosmetic ingredients, phytocompounds are generally milder, have a more favourable
toxicity profile, and are biodegradable. The major concerns in the usage of phytocompounds are their low solubility,
low penetration and physico-chemical instability when applied on the skin. To overcome these issues, different
nanotechnology-based systems have been proposed and some of them are already on the market. Nanotechnologies
can improve the solubility of poorly water-soluble compounds, facilitate skin permeation and increase
their stability against light and temperature. Liposomes, solid lipid nanoparticles, transfersomes, ethosomes,
nanostructured lipid carriers, and cyclodextrins are examples of nanotechnology-based systems currently in use to
improve the performances of phytocompounds in skin care. This review focuses on cosmeceuticals that explore
nanotechnology-based systems for the delivery of phytocompounds and emphasizes how these approaches can
improve product performances with respect to conventional cosmetic formulations.