The combination of magnetism and upconversion luminescent property into one single nanostructure is fascinating for biological fields, such as multimodal bioimaging, targeted drug delivery, and imaging-guided therapy. In this review, we will provide the state-of-the-art advances on magnetic upconversion nanocomposites towards their bioapplications. Their structure design, synthesis methods, surface engineering and applications in bioimaging, drug delivery, therapy as well as biodetection will be covered.
Keywords: Magnetic optical nanocomposite, upconversion luminescence, structure design, synthesis, surface modification, bioimaging, drug delivery, therapy.
Du B, Han S, Zhao F, et al. A smart upconversion-based lighttriggered polymer for synergetic chemo-photodynamic therapy and dual-modal MR/UCL imaging. Nanomed -Nanotechnol 2016; 12: 2071-80.
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