Graphene and graphene-based materials in biomedical applications

(E-pub Abstract Ahead of Print)

Author(s): Mohammad Omaish Ansari, Kalamegam Gauthaman, Abdurahman Eissa, Sidi A. Bencherif, Adnan Memic*.

Journal Name: Current Medicinal Chemistry

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Recently, there have been huge advancements in the field of nanobiotechnology. One of the main drivers has been the development of novel nanomaterials. One new class of materials is graphene and its derivatives recognized for their novel properties present on the nanoscale. In particular, graphene and graphene-based nanomaterials have been shown to have excellent electrical, mechanical, optical and thermal properties. Due to these unique properties coupled with the ability to tune their biocompatibility, these nanomaterials have been propelled for various applications. Most recently these two-dimensional nanomaterials have been widely recognized for their utility in biomedical research. In this review, we first give a brief overview of the strategies to synthesize graphene and its derivatives. Next, we discuss the biocompatibility profile of these nanomaterials as a precursor to their biomedical application. Finally, we highlight recent applications of graphene-based nanomaterials in various biomedical fields including tissue engineering, drug and gene delivery, biosensing and bioimaging as well as other bio-related studies.

Keywords: graphene, graphene oxide, tissue engineering, drug delivery, biomedical applications, biocompatibility, nanomaterials

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Article Details

(E-pub Abstract Ahead of Print)
DOI: 10.2174/0929867326666190705155854
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