Phytochemical and Pharmacological Review on Two Herbs of Baijiangcao: Patrinia scabiosaefolia Fisch. ex Trev. and Patrinia villosa (Thunb.) Juss

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Author(s): Yangcheng Liu , Wei Liu , Jiaqi Wang , Yang Liu , Changlan Chen* , Zheng Xiang* .

Journal Name: Mini-Reviews in Organic Chemistry

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Patrinia scabiosaefolia Fisch. ex Trev. and Patrinia villosa (Thunb.) Juss are two species of Patrinia recorded in Chinese pharmacopoeia with the same Chinese name “Baijiangcao” and similar therapeutic effect in traditional Chinese medicine. The present article is the first comprehensive review on the chemical composition and pharmacological activities of these herbs. In the present review, data on chemical constituents and pharmacological profile of the two herbs are given. This review discusses all the classes of 223 compounds (phenylpropanoids, flavonoids, terpenes, saponins and volatile components, etc.) detected in the two herbs providing information on the current state of knowledge of their phytochemicals of them. In the past three years, our research group has isolated and identified about more than 100 ingredients from the two herbs. Therefore, we published a systematic review of research papers we published and literatures about the two herbs were carried out using resources including classic books about Chinese herbal medicine and scientific data bases including Pubmed, Web of Science, SciFinder, CNKI. etc. The present review discusses the most thoroughly studied pharmacological activities (antioxidant, anti-inflammatory, immunomodulatory, antimicrobial, antitumor and antiviral activities.) of the two herbs. This comprehensive review will be informative for scientists searching for new properties of the two herbs and be important and significant for the discovery of bioactive compounds from the two herbs and full utilization of Patrinia scabiosaefolia Fisch. ex Trev. and Patrinia villosa (Thunb.) Juss

Keywords: Patrinia scabiosaefolia Fisch. ex Trev., Patrinia villosa (Thunb.) Juss, Phytochemical, Pharmacological.

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(E-pub Ahead of Print)
DOI: 10.2174/1570193X16666190617161124
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