Recent Advances in Palladium-Catalyzed Oxidative Cyclizations

Author(s): John C. Hershberger*.

Journal Name: Current Organic Chemistry

Volume 23 , Issue 9 , 2019

Become EABM
Become Reviewer

Graphical Abstract:


Abstract:

Heterocycles are very common substructures in a number of pharmaceuticals. Over the past several years, the use of palladium-catalyzed oxidative cyclization for heterocyclic synthesis has become much more prevalent. This review collects recent reports using palladium catalysis to synthesize a wide variety of heterocyclic scaffolds. Many of these reactions use oxygen as the terminal oxidant. Some salient mechanistic features are discussed.

Keywords: Oxidation, palladium, palladium-catalyzed, carbocycle, heterocycle, synthesis.

Rights & PermissionsPrintExport Cite as

Article Details

VOLUME: 23
ISSUE: 9
Year: 2019
Page: [1019 - 1044]
Pages: 26
DOI: 10.2174/1385272823666190429155004
Price: $58

Article Metrics

PDF: 14