Recent Advances in Palladium-Catalyzed Oxidative Cyclizations

Author(s): John C. Hershberger*.

Journal Name: Current Organic Chemistry

Volume 23 , Issue 9 , 2019

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Graphical Abstract:


Heterocycles are very common substructures in a number of pharmaceuticals. Over the past several years, the use of palladium-catalyzed oxidative cyclization for heterocyclic synthesis has become much more prevalent. This review collects recent reports using palladium catalysis to synthesize a wide variety of heterocyclic scaffolds. Many of these reactions use oxygen as the terminal oxidant. Some salient mechanistic features are discussed.

Keywords: Oxidation, palladium, palladium-catalyzed, carbocycle, heterocycle, synthesis.

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Article Details

Year: 2019
Page: [1019 - 1044]
Pages: 26
DOI: 10.2174/1385272823666190429155004
Price: $58

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