Emerging Biomedical Applications of Algal Polysaccharides

(E-pub Ahead of Print)

Author(s): Maryam Rahmati, Zahra Alipanahi, Masoud Mozafari*.

Journal Name: Current Pharmaceutical Design

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Background: Over the past two decades, there have been substantial progress and growing body of research on using natural polymeric biomaterials as drug delivery carries which is owing to their exceptional biocompatibility and biodegradability. Among different natural biopolymers, polysaccharides have gained considerable attraction among biomedical scientists and surgeons due to their biocompatibility, biodegradability, anti-inflammatory, and antimicrobial properties. In the recent years, algal-based polysaccharides including agar, alginate, and carrageenan, have been broadly suggested for different biological and biomedical applications.

Methods: The aim of this paper is discussing various possible applications of algal-based polysaccharides in biomedical applications particularly in controlled drug delivery systems. The main properties of each algal polysaccharide will be discussed. Additionally, particular drug delivery applications of each of them will be presented.

Results: Algal polysaccharides can be detected in a group of photosynthetic creatures as their key biomass constituents. They provide a range of variety in their sizes, shapes’ formation, liquefaction, chemical stability, and crosslinking ability. In addition, algal polysaccharides have exceptional gelling properties including stimuli-responsive behavior, softness, and swelling properties.

Conclusion: All the mentioned properties of alga polysaccharides lead to their successful usage in emerging biomedical applications specially targeted and controlled drug delivery systems such as particles, capsules, and gels.

Keywords: Sulfated Polysaccharide; Algae; hydrogel; Biomaterial; Biomedical; Drug Delivery

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(E-pub Ahead of Print)
DOI: 10.2174/1381612825666190423160357
Price: $95

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