An Update on the Use of Alginate in Additive Biofabrication Techniques

(E-pub Ahead of Print)

Author(s): Amoljit Singh Gill, Parneet Kaur Deol, Indu Pal Kaur*.

Journal Name: Current Pharmaceutical Design

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Abstract:

Background: Solid free forming (SFF) technique also called additive manufacturing (AM) process is immensely popular for biofabrication owing to its high accuracy, precision and reproducibility.

Method: SFF techniques like stereolithography, selective laser sintering, fused deposition modeling, extrusion printing, and inkjet printing create three dimension (3D) structures by layer by layer processing of the material. For getting desirable results, selection of the appropriate technique is an important aspect and it is based on the nature of biomaterial or bioink to be processed.

Result & Conclusion: Alginate is a commonly employed bioink in biofabrication process, attributable to its non-toxic, biodegradable and biocompatible nature; low cost; and tendency to form hydrogel under mild conditions. Further, control on its rheological properties like viscosity and sheer thinning, make this natural anionic polymer an appropriate candidate for many of the SFF techniques. It is endevoured in the present review to highlight the status of alginate as bioink in various SFF techniques.

Keywords: Stereolithography, selective laser sintering, fused deposition modeling, extrusion printing, inkjet printing, bioink

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Article Details

(E-pub Ahead of Print)
DOI: 10.2174/1381612825666190423155835
Price: $95