Hypertension in Obesity: Novel Insights

(E-pub Ahead of Print)

Author(s): Michail Natsis, Christina Antza, Ioannis Doundoulakis, Stella Stabouli, Vasilios Kotsis*.

Journal Name: Current Hypertension Reviews

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Background: The relationship between obesity and hypertension has been established in both adults and children. The combination of obesity, hypertension and other cardiovascular risk factors significantly increases the likelihood of adverse cardiovascular effects and raises concerns about aggressive treatment strategies.

Objective: Despite the impressive elements which indicate an important role for excessive weight gain in increasing blood pressure, not all obese patients are hypertensive. A subgroup of obese people may not develop hypertension. Furthermore, masked hypertension occurs more common among obese patients, and body fat distribution has a major role in the development of hypertension.

Methods: We conducted a research of the relevant literature regarding obesity-induced hypertension and possible treatment strategies.

Results: Successful weight loss is correlated with blood pressure reduction and requires a multidisciplinary approach that includes personalized dietary interventions combined with regular exercise and cognitive behavioral therapy.

Conclusion: Pharmacological therapy may be considered as part of a comprehensive obesity management strategy. More research and new treatment therapies are required in this field.

Keywords: obesity, hypertension, antiobesity drugs, obesity-induced hypertension, treatment, weight loss.

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(E-pub Ahead of Print)
DOI: 10.2174/1573402115666190415154603

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