Introduction: Increasing evidence supports the relationship between vitamin D and
stroke. Vitamin D has now been proposed as a prognostic biomarker also for functional outcome in
Method: A revision of the data suggests that low vitamin D is associated more with ischemic than
with haemorrhagic stroke, even if the role of optimal vitamin D levels for vascular wall is still unclear.
Vitamin D deficiency induces with different mechanisms an alteration of vascular wall.
Results: However, to date, the research supporting the effectiveness of vitamin D supplementation
in stroke and in post-stroke recovery is still inadequate and conclusive evidences have not been
Conclusion: In this review, we provide a better understanding of the role of vitamin D in stroke.