What is the Current Role for Vitamin D and the Risk of Stroke?

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Author(s): Antonio Siniscalchi*, Piergiorgio Lochner, Sabrina Anticoli, Domenico Chirchiglia, Luca Gallelli, Giovambattista De Sarro.

Journal Name: Current Neurovascular Research

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Introduction: Increasing evidence supports the relationship between vitamin D and stroke. Vitamin D has now been proposed as a prognostic biomarker also for functional outcome in stroke patients.

Method: A revision of the data suggests that low vitamin D is associated more with ischemic than with haemorrhagic stroke, even if the role of optimal vitamin D levels for vascular wall is still unclear. Vitamin D deficiency induces with different mechanisms an alteration of vascular wall.

Results: However, to date, the research supporting the effectiveness of vitamin D supplementation in stroke and in post-stroke recovery is still inadequate and conclusive evidences have not been published.

Conclusion: In this review, we provide a better understanding of the role of vitamin D in stroke.

Keywords: stroke, Vitamin D, biomarker, supplementation Vitamin D

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(E-pub Ahead of Print)
DOI: 10.2174/1567202616666190412152948
Price: $95

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