Pyrazolo[1,5-a]pyrimidines: A Close Look into their Synthesis and Applications

Author(s): Amal Al-Azmi*.

Journal Name: Current Organic Chemistry

Volume 23 , Issue 6 , 2019

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Graphical Abstract:


Abstract:

Pyrazolo[1,5-a]pyrimidines are fused N-heterocyclic systems of a pyrazole. They are considered as a key structural motif in many vital applications, such as medicinal, pharmaceuticals, pesticides, dyes and pigments. Their synthetic routes have escalated dramatically in the last decades. The current review is a recent synthetic survey of pyrazolo[ 1,5-a]pyrimidines and their applications until recently.

Keywords: Aminopyrazoles, pyrazoles, pyrimidines, MCR, anticancer, heterocylces, antibacterial.

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VOLUME: 23
ISSUE: 6
Year: 2019
Page: [721 - 743]
Pages: 23
DOI: 10.2174/1385272823666190410145238
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