Login Register Cart 0
Generic placeholder image

Current Respiratory Medicine Reviews

Editor-in-Chief

ISSN (Print): 1573-398X
ISSN (Online): 1875-6387

Back
Journal Home About Journal Editorial Board Journal Insight Current Issue Volumes/Issues
Subscribe
Research Article

Differences Between COPD Patients of a Pulmonary Rehabilitation Program According to the mMRC Dyspnea Scale

Author(s): Jhonatan Betancourt-Peña, Vicente Benavides-Córdoba*, Juan Carlos Avila-Valencia and Hamilton Elias Rosero-Carvajal

Volume 15, Issue 1, 2019

Page: [32 - 38] Pages: 7

DOI: 10.2174/1573398X15666190404150703

Abstract

Background: The modified Medical Research Council scale (mMRC) is a standardized measure of the effect of dyspnea on the activities of the daily life of patients suffering from Chronic Obstructive Pulmonary Disease (COPD). The aim of this study was to determine the differences in the quality of life, tolerance to effort and symptoms among patients with COPD with lower (mMRC 0-1) and greater symptoms (mMRC ≥2).

Methods: Cross-sectional study that included patients admitted to a pulmonary rehabilitation program and who were classified into 2 groups: a group containing the less symptomatic patients and another group with the more symptomatic ones. We collected these patients’ sociodemographic, clinical, anthropometric, anxiety, depression and quality of life (SGRQ) data. Likewise, the subjects performed the 6-minute walk test (6MWT). Finally, we measured the multidimensional BODE index score.

Results: 130 subjects were included, 35 presenting an mMRC of 0 to1 and 95 having an mMRC ≥ 2, with an age of 70.87 ± 9.45 years old. The 6MWT distance, the VO2e, the total score of SGRQ, and its domains of activities and impact showed significant differences between the groups (p <0.05). Significant correlations were found in the group presenting an mMRC of 0-1 between the mMRC and the FEV1 (p = 0.028), and in the group with an mMRC ≥2 for the FVC (p = 0.031), the 6MWT distance (p = 0.000), the VO2e (p = 0.010) and the BODE index (p = 0.000).

Conclusion: Patients with an mMRC of 0 to1 had better results in the 6MWT, the VO2e and the SGRQ in comparison with the most symptomatic ones.

Keywords: Chronic obstructive pulmonary disease, dyspnea, exercise tolerance, quality of life, patients, pulmonary rehabilitation program.

« Previous Next »
Graphical Abstract

[1]
Global Strategy for the Diagnosis, Management and Prevention of COPD - Global Initiative for Chronic Obstructive Lung Disease - GOLD.. 2019.
[2]
O’Donnell DE, Gebke KB. Activity restriction in mild COPD: A challenging clinical problem. Int J Chron Obstruct Pulmon Dis 2014; 9: 577-88.
[3]
Liu Y, Pleasants RA, Croft JB, et al. Smoking duration, respiratory symptoms, and COPD in adults aged >/=45 years with a smoking history. Int J Chron Obstruct Pulmon Dis 2015; 10: 1409-16.
[4]
Gallego MC, Samaniego J, Alonso J, Sánchez A, Carrizo S, Marín JM. Disnea en la EPOC: Relación de la escala MRC con la disnea inducida en las pruebas de marcha y de ejercicio cardiopulmonar máximo. Arch Bronconeumol 2002; 38(3): 112-6.
[5]
Parshall MB, Schwartzstein RM, Adams L, et al. An official American Thoracic Society Statement: Update on the mechanisms, assessment, and management of Dyspnea. Am J Respir Crit Care Med 2012; 185(4): 435-52.
[6]
Spruit MA, Singh SJ, Garvey C, et al. An official American Thoracic Society/European Respiratory Society statement: Key concepts and advances in pulmonary rehabilitation. Am J Respir Crit Care Med 2013; 188(8): e13-64.
[7]
Lacasse Y, Martin S, Lasserson TJ, Goldstein RS. Meta-analysis of respiratory rehabilitation in chronic obstructive pulmonary disease. A Cochrane systematic review. Eura Medicophys 2007; 43(4): 475-85.
[8]
American College of Sports Medicine. ACSM’s guidelines for exercise testing and prescription.Ninth Edition. Lippincott, Williams & Wilkins 2014.
[9]
Holland AE, Spruit MA, Troosters T, et al. An official European Respiratory Society/American Thoracic Society technical standard: Field walking tests in chronic respiratory disease. Eur Respir J 2014; 44(6): 1428-46.
[10]
Celli BR, Cote CG, Marin JM, et al. The body-mass index, airflow obstruction, dyspnea, and exercise capacity index in chronic obstructive pulmonary disease. N Engl J Med 2004; 350(10): 1005-12.
[11]
Ferrer M, Villasante C, Alonso J, et al. Interpretation of quality of life scores from the St George’s Respiratory Questionnaire. Eur Respir J 2002; 19(3): 405-13.
[12]
Terol-Cantero MC, Cabrera-Perona V, Martín-Aragón M. Hospital Anxiety and Depression Scale (HADS) review in Spanish Samples. An Psicol-Spain 2015; 31(2): 494-503.
[13]
Boland MR, Tsiachristas A, Kruis AL, Chavannes NH, Rutten-van Molken MP. Are GOLD ABCD groups better associated with health status and costs than GOLD 1234 grades? A cross-sectional study. Prim Care Respir J 2014; 23(1): 30-7.
[14]
Mapel DW, Dalal AA, Johnson PT, Becker LK, Hunter AG. Application of the new GOLD COPD staging system to a US primary care cohort, with comparison to physician and patient impressions of severity. Int J Chron Obstruct Pulmon Dis 2015; 10: 1477-86.
[15]
Rugbjerg M, Iepsen UW, Jorgensen KJ, Lange P. Effectiveness of pulmonary rehabilitation in COPD with mild symptoms: A systematic review with meta-analyses. Int J Chron Obstruct Pulmon Dis 2015; 10: 791-801.
[16]
Cameron-Tucker HL, Wood-Baker R, Owen C, Joseph L, Walters EH. Chronic disease self-management and exercise in COPD as pulmonary rehabilitation: A randomized controlled trial. Int J Chron Obstruct Pulmon Dis 2014; 9: 513-23.
[17]
Hjalmarsen A, Brenn T, Jongsma Risberg M, Meisler Antonsen K, Kristiansen Benum E, Aaseboe U. Retrospective survival in elderly COPD patients receiving pulmonary rehabilitation; A study including maintenance rehabilitation. BMC Res Notes 2014; 7: 210.
[18]
Benavides V, Wilches-Luna E. Cambios en la puntuación del índice bode en pacientes con enfermedad pulmonar obstructiva crónica antes y después de rehabilitación pulmonar. Revista Ciencias de la Salud 2018; 16(1): 101-13.
[19]
Osterling K, MacFadyen K, Gilbert R, Dechman G. The effects of high intensity exercise during pulmonary rehabilitation on ventilatory parameters in people with moderate to severe stable COPD: A systematic review. Int J Chron Obstruct Pulmon Dis 2014; 9: 1069-78.
[20]
Boissiere L, Perotin-Collard JM, Bertin E, et al. Improvement of dyspnea after bariatric surgery is associated with increased Expiratory Reserve Volume: A prospective follow-up study of 45 patients. PLoS One 2017; 12(9): e0185058.
[21]
Demeyer H, Burtin C, Van Remoortel H, et al. Standardizing the analysis of physical activity in patients with COPD following a pulmonary rehabilitation program. Chest 2014; 146(2): 318-27.
[22]
Betancourt-Peña J, Tonguino-Rosero S, Rosero-Carvajal HE, Hurtado H. Diferencias de la rehabilitación pulmonar en pacientes con EPOC, con y sin indicación de oxígeno domiciliario a largo plazo. Fisioterapia 2018; 40(4): 167-222.
[23]
Jacome C, Marques A. Short- and Long-term effects of pulmonary rehabilitation in patients with mild COPD: A comparison with patients with moderate to seveRE COPD. J Cardiopulm Rehabil Prev 2016; 36(6): 445-53.
[24]
Parada A, Klaassen J, Lisboa C, Saldias F, Mendoza L, Diaz O. [Reduction of physical activity in patients with chronic obstructive pulmonary disease]. Rev Med Chil 2011; 139(12): 1562-72.
[25]
López Varela MV, Anido T, Larrosa M. Estado funcional y supervivencia de los pacientes con EPOC tras rehabilitación respiratoria. Arch Bronconeumol 2006; 42(9): 434-9.
[26]
Spruit MA, Watkins ML, Edwards LD, et al. Determinants of poor 6-min walking distance in patients with COPD: The ECLIPSE cohort. Respir Med 2010; 104(6): 849-57.
[27]
Kaymaz D, Candemir IC, Ergun P, Demir N, Tasdemir F, Demir P. Relation between upper-limb muscle strength with exercise capacity, quality of life and dyspnea in patients with severe chronic obstructive pulmonary disease. Clin Respir J 2018; 12(3): 1257-63.
[28]
Morishita-Katsu M, Nishimura K, Taniguchi H, et al. The COPD assessment test and St George’s Respiratory Questionnaire: Are they equivalent in subjects with COPD? Int J Chron Obstruct Pulmon Dis 2016; 11: 1543-51.
[29]
Betancourt-Peña J, Muñoz BE, Mora-Guerra RV. Calidad de vida en pacientes con enfermedad Pulmonar obstructiva crónica al ingreso de Un programa de rehabilitación pulmonar. Rev Col Rehab 2015; 14(1): 46-53.
[30]
Patel A. Correlation of spirometry with six minute walk test and grading of dyspnea. Eur Respir J 2015; 46: PA604.
[31]
A. Attia G. Correlation of respiratory pump function with symptomatology in COPD. Egypt J Chest Dis Tuberc 2016; 65(1): 35-40.

Rights & Permissions Print Cite
Article Metrics
12
2
1
1
© 2024 Bentham Science Publishers | Privacy Policy